Monilethrix
نویسنده
چکیده
MONILETHRIX, or "beading of the hair" (Fig. 1)* is a rare inherited abnormality in the formation of hair. It was first reported by Smith (1879) and named by' Crocker. The cohdition; is cotnnfonly fa-milial, although isolated non-familial cases have been recorded;-The scalp'hAir is' usually affected, biut many patients showing monilethrix of the pubic and axillary hair and of the eyebrows and eyelashes have been seen. Hyperkeratosis of mouths of follicles is a usual accompaniment, but is not invariably found. It is, however, present in our family. Other congenital abnormalities, particularly of teeth and nails, may be associated, but usually affected people are healthy and their physique good (Cockayne, 1933).
منابع مشابه
Treatment of monilethrix with oral minoxidil
Fig 1. Patient 1. Dermascopic image of the occipital scalp shows numerous broken hairs. Beaded hairs pathognomic of monilethrix can be seen. INTRODUCTION Monilethrix is an autosomal dominant genodermatosis characterized by hair fragility, keratosis pilaris, and pathognomonic beading of the hair shaft. Hair fragility may lead to hair breakage and the appearance of generalized hair loss. The gene...
متن کاملA mutation in the type II hair keratin KRT86 gene in a Han family with monilethrix☆
Monilethrix, a congenital disease of hair, is usually associated with mutations in keratin genes, like KRT81, KRT83 and KRT86. We conducted this study to investigate the mutation of type II human basic hair keratin hHb/KRT gene in a Han family with monilethrix and obtain information for potential pathogenic mechanism study of monilethrix. Peripheral blood samples were drawn for genomic DNA dete...
متن کاملMoniletherix
Monilethrix is an autosomal dominant hair shaft disorder characterized by intermittent constrictions result in short and fragility hair. We present here two afghan siblings girl, 5 and 3 years, born of consanguineous marriage, come to our department of dermatology with complains of hair loss and inability to growth long hair of the scalp since birth. When the hairs reached a certain length, the...
متن کاملMonilethrix: a typical case report with microscopic and dermatoscopic findings*
Monilethrix is a rare hereditary condition generally considered to be an autosomal dominant disorder with variable penetrance. A case of a 6-year-old girl without a familial background for this disease is reported. The diagnosis was made by optic microscopy and dermoscopy. A therapeutic trial with topical minoxidil was conducted.
متن کاملComment on: Serum Vitamin D3 Levels and Diffuse Hair Fall among the Student Population in South India: A Case–control Study
1. Ferrando J, Galve J, Torres‐Puente M, Santillán S, Nogués S, Grimalt R. Monilethrix: A new family with the novel mutation in KRT81 gene. Int J Trichology 2012;4:53‐5. 2. Arif T, Majid I, Ishtiyaq Haji ML, Samoon N. Monilethrix – Case report of a rare disease. Our Dermatol Online 2015;6:46‐8. 3. Redler S, Pasternack SM, Wolf S, Stienen D, Wenzel J, et al. A novel KRT86 mutation in a Turkish f...
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ورودعنوان ژورنال:
- The Ulster Medical Journal
دوره 25 شماره
صفحات -
تاریخ انتشار 1956